Molecular Imaging with Targeted Contrast Ultrasound
نویسندگان
چکیده
منابع مشابه
Molecular imaging with targeted contrast agents.
Molecular imaging with targeted contrast agents by magnetic resonance imaging (MRI) allows for the noninvasive detection and characterization of biological changes on a molecular level. In this article, the principles of molecular MRI and its applications in cardiovascular diseases are reviewed. First, basic properties of positive and negative contrast agents are introduced and their effect on ...
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Methods for imaging the molecular or cellular profile of tissue are being developed for all forms of non-invasive cardiovascular imaging. It is thought that these technologies will potentially improve patient outcomes by allowing diagnosis of disease at an early-stage, monitoring disease progression, providing important information on patient risk, and for tailoring therapy to the molecular bas...
متن کاملMolecular and Cellular Imaging with Ultrasound Contrast Agents
Introduction Today, ultrasound imaging generally plays a minor role in molecular imaging. Most of the clinical activities are focused on PET and SPECT, and most of preclinical research is expanded to the areas of optical imaging and MRI. However, with proper contrast agents designed for molecular imaging, ultrasound can play an essential role both in research and clinical applications. Historic...
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AIMS Imaging methods to track the fate of progenitor cells after their delivery would be useful in assessing the efficacy of cell-based therapies. We hypothesized that contrast-enhanced ultrasound (CEU) using microbubbles targeted to a genetically engineered cell-surface marker on endothelial progenitor cells (EPCs) would allow the targeted imaging of vascular engraftment. METHODS AND RESULTS...
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Targeted ultrasound contrast materials (gas-filled microbubbles carrying ligands to endothelial selectins or integrins) have been investigated as potential molecular imaging agents. Such microbubbles normally exhibit good targeting capability at the slower flow conditions. However, in the conditions of vigorous flow, binding may be limited. Here, we describe a microbubble capable of efficient b...
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ژورنال
عنوان ژورنال: Cerebrovascular Diseases
سال: 2009
ISSN: 1421-9786,1015-9770
DOI: 10.1159/000203128